High-Dose IV Vitamin C
In cell cultures, Vitamin C has been found to be cytotoxic against cancer. Cytotoxic means that it kills cancer cells, but not healthy cells.
To be effective, very large doses are required. In Japan, the “Rirodan” protocol is used for cancer patients, with doses as high as 100 grams, with great success. I use between 50 and 75 grams per treatment.
You need a blood test to determine the correct amount. Per Dr. Riordan (who succeeded Linus Pauling, a pioneer in orthomolecular medicine, in studying the impact of high-dose Vitamin C as a cancer therapy), the ideal target for cancer patients is post treatment levels of 350-400 milligrams per deciliter. Studies have shown that, when used in conjunction with chemotherapeutic agents, high-dose Vitamin C reduces side effects and enhances the benefit of the treatment itself.
In my view, the most significant therapeutic benefit from this protocol results from the “redox” effect. Like hormesis (where something, like stress or exercise, benefits the body), redox is an example of the “ebb and flow” cycling effect that is a hallmark of life. The cells go through a cycle of “oxidation” (when molecules lose electrons), and “reduction” (when they get those electrons back). This cycling is necessary for health. Oxidation, in a healthy environment, and with healthy cells, is a necessary signal for the mitochondria to generate ATP. The flow of these electrons must occur in the right part of the membrane, at the right time, and it the right amounts. This is redox.
In addition, reactive oxygen species are signaling molecules for apoptosis (cell death).
Vitamin C assists in both ends of the redox process. In high doses, Vitamin C has pro-oxidant impacts by its effect on the interaction of oxygen and iron in the tissues, which generates hydrogen peroxide. In addition, Vitamin C provides electrons for the cells, which supports reduction.
Most studies focus on the anti-oxidant benefits of high-dose Vitamin C, which is worthwhile. But it is this “redox dance” that takes place at the cellular level where the magic occurs, improving outcomes and reducing side effects of other therapies.
Talk to your integrative or functional doctor about using ozone treatment followed by high-dose Vitamin C (on different days), as a one-two punch to assist the body in terminating malfunctioning cells.
Words of caution: most of the vitamin C on the market is manufactured from the fermentation of corn, which is likely GMO and contaminated with Glyphosate and mycotoxins. Be sure your practitioner is using non-corn based vitamin C.
Artesunate, which is derived from the wormwood tree, is a drug commonly used for malaria. More recently, it has been adopted in a multi-modal approach to addressing cancer. In fact, its use is expanding to include standard-of-care, where it has been found to be improve outcomes when used in combination with chemotherapy.
Artesunate is another cytotoxic agent.
The mechanism of its use in cancer therapy is clear. Cancer cells tend to absorb high levels of iron, and this accelerate cellular mutation, as iron reacts with oxygen to form free radicals (see the discussion above on high-dose Vitamin C). These reactive molecules then damage DNA. Artesunate activates mitochondrial apoptosis by producing “iron catalyzed” lysosomal reactive oxygen species.
Per studies done at the Integrative Oncology Research Center at Bastyr University, doses of IV Artesunate in conjunction with high-dose Vitamin C, together, provide significant benefits for breast-cancer patients. After two years of treatments, those patients getting the “combined IV” treatments had a 90% survival rate, while the control group had a 68% survival rate).
I have been doing IV Artesunate prior to high dose Vitamin C IV treatment (same day). Talk to your health-care practitioner about this combination.
Glutathione is powerful anti-oxidant that is produced in the liver and the lungs, and can be sourced from food and supplements. Standard of care doctors may prescribe intravenous glutathione to cancer patients to reduce the toxic side effects of chemotherapy. As the “master anti-oxidant” it has become very popular in the anti-aging community. As we age, our bodies produce less and less glutathione.
Supplementation with capsules or transdermally are not likely to have much, if any impact. The best way to make sure it gets into the system is to take it intravenously. I take it for the support it provides to the immune system and for supporting cellular functioning.
Note that you cannot take glutathione the same day as taking high-dose Vitamin C.
Other possible IV and intra-muscular injection treatments include CBD oil, Viscum (mistletoe) and GcMAF, which will be addressed in future blogposts.